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Confocal microscopy and imaging profilometry: A new tool aimed to evaluate aesthetic procedures.

Fabbrocini G, Mazzella C, Montagnaro F, De Padova MP, Lorenzi S, Tedeschi A, Forgione P6, Capasso C, Sivero L, Velotti C, Russo D, Vitiello R, Ilardi G. J Cosmet Laser Ther. 2017 Feb;19(1):59-63. doi: 10.1080/14764172.2016.1247962.

ABSTRACT

According to the American Academy of Aesthetic Plastic Surgeons, more than 11 million cosmetic surgical and nonsurgical procedures were performed by board-certified plastic surgeons, dermatologists and otolaryngologists in the United States, totaling more than 12 billion dollars. We performed a retrospective observational multi-centric study on patients treated with a non-animal origin cross-linked hyaluronic acid with different molecular weights for nasolabial folds, evaluating through a new imaging system, profilometric techniques with the confocalmicroscopy, the durability, the efficacy and the safety of this product. From 25 patients, 150 silicone casts were obtained: 75 casts of the right nasolabial fold and 75 casts of the left nasolabial fold. Roughness arithmetical average of the right fold at T2 decreased by 50% versus T0 and by 40% compared to T1; at T2, it decreased by the 45% versus T0 and by 35% compared to T1. No side effects were reported. Results proved that the analysis of the skin microreliefs through confocal microscopy is a new imaging system that allows to evaluate with precision and safety the results of aesthetic treatments such as fillers objectively.

KEYWORDS:Confocal microscopy; hyaluronic acid fillers; profilometry

PMID: 27911109 

DOI: 10.1080/14764172.2016.1247962

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